Biological System
Hematologic Adaptation
Changes in blood cell populations and function
Overview
Blood is a living tissue. Red blood cells carry oxygen; platelets clot wounds; white cells fight infection. In microgravity, plasma volume shifts and red blood cell production adapts to reduced cardiovascular demand. The Inspiration4 CBC data captures these changes across seven timepoints spanning 286 days.
Key findings
- Hemoglobin and hematocrit showed modest early post-flight changes consistent with fluid redistribution.
- Platelet counts were variable across crew members — individual differences dominated over any flight effect.
- RBC indices (MCV, MCH, MCHC) remained largely within reference ranges for all crew members.
- All fold-changes reported relative to each individual's L-44 baseline draw.
Individual trajectories
fold-change from L-44 baseline · n=4n=4 crew members. Reference band drawn from _range_min / _range_max columns in the CBC data file.
Hematologic Adaptation · C001
● Trajectory chart renders after preprocessing
Hematologic Adaptation · C002
● Trajectory chart renders after preprocessing
Hematologic Adaptation · C003
● Trajectory chart renders after preprocessing
Hematologic Adaptation · C004
● Trajectory chart renders after preprocessing
Related dashboard domains
How to read this page: These findings describe four individuals at one point in time. No finding should be generalized to spaceflight health broadly. Individual differences dominate the signal. Fold-changes labeled “2× individual baseline” use derived thresholds, not clinical cutoffs.